RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
Running, not enrolling · Not applicable
Conditions studied: Cardiac Arrest
In brief
RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest. RACE-CARS will enroll 50 counties in North Carolina that are estimated to have a total of approximately 20,000 patients with cardiac arrest over a 4-year intervention period. County "clusters" will be randomized in a 1:1 ratio to intervention versus usual care. The trial duration is 7 years, which includes a 6-month start-up (including recruitment and randomization) period, a 12-month intervention training phase, a 4-year intervention period, a 12-month follow-up for to assess quality of life in survivors of OHCA, and a 6-month close-out and data analysis period.
Key facts
- Study ID
- NCT04660526
- Run by
- Duke University
- People needed
- 20000
- Starts
- 2022-07-01
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-07-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- OHCA of non-traumatic etiology
- Patients who are pulseless on arrival of a first responder; or patients who become pulseless in the presence of a first responder; OR patients who have a pulse on arrival of EMS, where a successful defibrillation was previously administered by a bystander or first responder.
You may not qualify if…
- Untreated cardiac arrests, including arrests in which resuscitation efforts are not initiated or are terminated immediately upon arrival of EMS because the patient is not a viable candidate for resuscitation due to:
- injuries incompatible with life,
- the presence of rigor mortis or lividity,
- signs of decomposition, or
- the presence of a valid DNR.
- Private EMS transport that did not involve 911 dispatch (example: interfacility transport between nursing home and hospital).
- Arrest of clear and obvious traumatic etiology
- Bystander suspected cardiac arrest, where ROSC was achieved without the need for defibrillation or first responder CPR
Where it is running
- Duke — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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