Study of Iron Accumulation Measured in MRI in Non-pathological Aging

Recruiting now

Conditions studied: Healthy Aging

In brief

To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

Key facts

Study ID

NCT04659824

Run by

University Hospital, Lille

People needed

190

Starts

2023-01-30

Expected to finish

2029-01-01

Last updated by the study team

2025-05-29

Who can join

Age: 18 and older, up to 95. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men or women between 18 and 95 years old
• French speaker with capability to understand the instructions
• Health insurance

You may not qualify if…

• Pregnancy
• minor subject
• no informed consent agreement
• subject enrolled in pharmaceutic study or exclusion period
• MRI contra-indications
• Neurological or psychiatric disorders
• MOCA < 26
• Psychotropic drugs
• More than 3 MRI exams
• More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months
• Unable to follow the entire protocol according to the investigator

Where it is running

• Hopital Roger Salengro, CHU Lille — Lille, France (enrolling)

Full record on ClinicalTrials.gov

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