Prospective Study on Patients With Obstructive Sleep Apnea in Hong Kong (PrOSA)
Recruiting now
Conditions studied: Obstructive Sleep Apnea
In brief
Obstructive sleep apnea syndrome (OSAS) is a common disorder with prevalence rates of at least 4% among the middle-aged male Caucasians and Hong Kong (HK) Chinese populations. It is characterized by repetitive episodes of upper airway obstruction, causing intermittent hypoxia, sleep fragmentation, disabling daytime sleepiness, impaired cognitive function and poor health status. OSAS patients are at increased risks of non-fatal and fatal cardiovascular morbidity and mortality including sudden death, in addition to being more prone to road traffic accidents. However, there is no long term follow up of patients with OSAS on the incidence of cardiovascular disease, compliance on the therapy and the impact of the quality of life. The study is aimed to carry out a prospective observational study assessing the role of OSAS as a possible cause of increased cardiovascular risk and cognitive decline.
Key facts
- Study ID
- NCT04659291
- Run by
- Chinese University of Hong Kong
- People needed
- 1000
- Starts
- 2020-08-30
- Expected to finish
- 2028-08-29
- Last updated by the study team
- 2024-02-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- suspected obstructive sleep apnea syndrome
- aged 18 or above
- must be able to speak, read and understand Chinese or English
- possess the ability to respond to questions and follow instructions.
You may not qualify if…
- already treated sleep apnea,
- a limited life expectancy due to illness unrelated to sleep apnea
- human immunodeficiency virus (HIV),
- advanced renal disease,
- uncontrolled malignancies
- documented alcohol or drug abuse up to 1 year prior to inclusion in the study.
Where it is running
- Chinese University of Hong — Hong Kong, Please Select, Hong Kong (enrolling)
Full record on ClinicalTrials.gov
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