A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Recruiting now · Phase 1/Phase 2
Conditions studied: Advanced Cancer, Metastatic Cancer, Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer, Endometrial Cancer, Metastatic Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Acinar Cell Carcinoma
In brief
This clinical trial is evaluating a drug called ART0380 in participants with advanced or metastatic solid tumors. The main goals of this study are to: * Find the recommended dose of ART0380 that can be given safely to participants alone and in combination with gemcitabine or irinotecan * Learn more about the side effects of ART0380 alone and in combination with gemcitabine or irinotecan * Learn more about the effectiveness of ART0380 alone and in combination with gemcitabine or irinotecan
Key facts
- Study ID
- NCT04657068
- Run by
- Artios Pharma Ltd
- People needed
- 542
- Starts
- 2021-01-27
- Expected to finish
- 2028-06-01
- Last updated by the study team
- 2026-07-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic (Arizona) — Scottsdale, Arizona, United States (enrolling)
- University of Alabama at Birmingham — Birmingham, Alabama, United States (enrolling)
- USC Norris Comprehensive Cancer Center — Los Angeles, California, United States (enrolling)
- Sansum Clinic — Santa Barbara, California, United States (enrolling)
- University of Arkansas - Winthrop P. Rockefeller Cancer Institute — Little Rock, Arkansas, United States (enrolling)
- Rocky Mountain Cancer Center — Denver, Colorado, United States (enrolling)
- Sarah Cannon Research Institute at HealthONE — Denver, Colorado, United States (enrolling)
- Florida Cancer Specialists — Fort Myers, Florida, United States (enrolling)
- Mayo Clinic (Florida) — Jacksonville, Florida, United States (enrolling)
- Cancer Specialists of North Florida — Jacksonville, Florida, United States (enrolling)
- Providence Medical Foundation — Santa Rosa, California, United States (enrolling)
- Florida Cancer Specialists — Sarasota, Florida, United States (enrolling)
- Florida Cancer Specialists — West Palm Beach, Florida, United States (enrolling)
- Hope and Healing Cancer Services — Hinsdale, Illinois, United States (enrolling)
- Community Health Network — Indianapolis, Indiana, United States (enrolling)
- Our Lady of the Lake — Baton Rouge, Louisiana, United States (enrolling)
- Maryland Oncology Hematology - Primary — Columbia, Maryland, United States (enrolling)
- Minnesota Oncology Hematology — Maple Grove, Minnesota, United States (enrolling)
- Mayo Clinic (Minnesota) — Rochester, Minnesota, United States (enrolling)
- Washington University — St Louis, Missouri, United States (enrolling)
- Hematology Oncology Associates of Central New York — East Syracuse, New York, United States (enrolling)
- Northwell Health Cancer Institute — Lake Success, New York, United States (enrolling)
- Oncology Hematology Care Primary — Cincinnati, Ohio, United States (enrolling)
- Taylor Cancer Research Center — Maumee, Ohio, United States (enrolling)
- Stephenson Cancer Center — Oklahoma City, Oklahoma, United States (enrolling)
Full record on ClinicalTrials.gov
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