Behavior Therapy for Irritability in Autism

Completed · Not applicable

Conditions studied: Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger, Aggression, Asperger Syndrome, Pervasive Developmental Disorder

In brief

This is a clinical trial of a novel intervention, Behavioral Therapy for Irritability and Aggression (BTIA), for adolescents on the autism spectrum. The main goals of BTIA are to help adolescents develop emotion regulation skills to handle frustration and to strengthen skills for navigating the challenging and diverse experiences associated with the transition to adulthood. The study will test whether BTIA can be helpful to adolescents on the autism spectrum and to their families.

Key facts

Study ID

NCT04654260

Run by

Yale University

People needed

65

Starts

2020-12-10

Expected to finish

2026-05-01

Last updated by the study team

2026-06-12

Who can join

Age: 12 and older, up to 19. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Boys and girls, ages 12 to 18 years inclusive
• Diagnosis of autism spectrum disorder
• Presence of disruptive behaviors such as irritability and anger outbursts
• No planned changes in the intensity of current treatment(s)
• Medication free or on stable medication
• Sufficient language for participation in verbal therapy
• Lives within driving distance from New Haven, CT

You may not qualify if…

• Presence of a medical condition that would interfere with participation in the study
• Presence of a current psychiatric disorder that requires immediate clinical attention

Where it is running

• Yale Child Study Center — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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