Resilience-based Psychosocial Intervention Among Children Affected by HIV/AIDS

Completed · Not applicable

Conditions studied: Emotional Adjustment, Aids/Hiv Problem

In brief

Parental illness and death from HIV/AIDS has a profound and lasting impact on a child's psychosocial well-being, potentially challenging the basic needs for survival and compromising the child's future. Therefore, the impact of parental HIV/AIDS on children needs to be treated from both a public health and a developmental perspective. However, to date the role of a resilience-based approach among children affected by HIV is hypothesized but not evidence-based. In this application, we propose to develop a theory-guided, resilience-based, multimodal intervention by culturally adapting and integrating components from three SAMHSA model programs which show strong evidence in promoting protective factors among young children. The multimodal intervention will include three approach levels: the individual child (peer-group activities), the family (caregiver parenting skill training), and the local community (community advocacy). The short, medium, and long-term efficacy of the Child-Caregiver-Advocacy-Resilience \[ChildCARE\] intervention to improve health and psychosocial well-being of children will be evaluated over 36 months through a cluster randomized controlled trial. About 800 HIV/AIDS-affected children (8 to 11 years of age) and their primary caregivers will be recruited from central China where we have built a strong research infrastructure and community collaboration during our previous study. The primary outcome measures for the children will include physical health, mental health, growth and development, school performance, and a biological indicator of neurobiological stress response (salivary cortisol). The outcome measures at caregiver level will include parenting style, parental engagement, and mental health well-being. The changes at the community level will be measured using children's and caregivers' perceptions of social support and HIV-related public stigma. We will also examine the potential mechanism through which the ChildCARE intervention is exerting its impact by identifying improvement in protective factors and other individual and contextual factors that potentially mediate or moderate the intervention effect. This proposed project will examine whether the multilevel protective factors we identified in our initial project are amenable to intervention and whether their hypothesized changes explain improvement in children outcomes.

Key facts

Study ID

NCT04653441

Run by

University of South Carolina

People needed

790

Starts

2011-09-15

Expected to finish

2017-07-30

Last updated by the study team

2020-12-04

Who can join

Age: 8 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 8 to 17 years of age
• having lost one or both parent to AIDS (orphans) or are currently living with a HIV-positive parent (vulnerable children)

You may not qualify if…

• children living in centralized care setting;
• known HIV-infection;
• physical illness and developmental disability (e.g., severe mental retardation) that prevent them from engaging routine daily activities;
• plan to permanently relocate outside of the province within a year.

Where it is running

• University of South Carolina — Columbia, South Carolina, United States

Full record on ClinicalTrials.gov

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