The Effect of Facial Effleurage on Acute Rhinosinusitis

Completed · Not applicable · Has a placebo group

Conditions studied: Rhinosinusitis Acute

In brief

Rhinosinusitis accounts for 12% of the total antibiotic prescriptions filled in the United States annually; however, the majority of rhinosinusitis cases have been proposed to have a viral etiology, or are capable of spontaneously resolving. This overuse of antibiotics is contributing to the development of antibiotic-resistant human pathogenic bacteria, and increasing patient mortality to previously easily cured diseases. This is also causing an unnecessary financial burden especially for uninsured, rural families. Facial Effleurage (FE) is an osteopathic manipulative therapy that allows physicians an alternative therapy to prescribing antibiotics; however, the only scientific literature on the technique is weak in design and execution. This will be a randomized, placebo-controlled clinical trial to test the ability of FE to reduce symptom severity over time, reduce the cellular infiltrate into the nasal cavity, and to more quickly resolve the symptoms of rhinosinusitis compared to antibiotic treatment. This methodical approach to the efficacy of FE has the potential to impact the treatment recommendations of physicians immediately, and to convince more physicians to prescribe less antibiotics and rely more heavily on FE.

Key facts

Study ID

NCT04642989

Run by

Edward Via Virginia College of Osteopathic Medicine

People needed

138

Starts

2018-09-01

Expected to finish

2020-09-01

Last updated by the study team

2020-11-24

Who can join

Age: 18 and older, up to 69. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Presents with no acute disease OR
• Presents with anterior/posterior mucopurulent drainage and nasal obstruction/facial pain/pressure/fullness
• Independently and without coercion read, understood, and signed the informed consent form
• Is between 18-69 years old.

You may not qualify if…

• History of: cancer, HIV, HIV exposure, osteoporosis, acute hepatitis, cystic fibrosis, type-1 diabetes, taking insulin for diabetes, deep vein thrombosis, pulmonary embolism
• History of recent trauma to the liver or spleen or surgery within the past 6 months
• Currently pregnant or nursing
• Have a comorbidity that requires antibiotics or antiviral therapy
• Have a fever greater than 102.5F
• Used topical antimicrobials in the past 30 days
• Taken oral antimicrobials in the past 15 days
• Participated in a clinical trial in the past 6 months
• Have current face or neck bone fractures
• Have abscesses, incisions, or nasal polyps visible on physical examination
• Need to be hospitalized for any reason

Where it is running

• Edward Via College of Osteopathic Medicine — Spartanburg, South Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.