BoMI for Muscle Control
Status unconfirmed · Not applicable
Conditions studied: Spinal Cord Injury Cervical, Stroke
In brief
People with spinal cord injury (SCI), stroke and other neurodegenerative disorders can follow two pathways for regaining independence and quality of life. One is through clinical interventions, including therapeutic exercises. The other is provided by assistive technologies, such as wheelchairs or robotic systems. In this study, we combine these two paths within a single framework by developing a new generation of body-machine interfaces (BoMI) supporting both assistive and rehabilitative goals. In particular, we focus on the recovery of muscle control by including a combination of motion and muscle activity signals in the operation of the BoMI.
Key facts
- Study ID
- NCT04641793
- Run by
- Shirley Ryan AbilityLab
- People needed
- 60
- Starts
- 2020-01-20
- Expected to finish
- 2024-08-01
- Last updated by the study team
- 2020-11-24
Who can join
Age: 16 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Ages 18 and up.
- Ability to follow simple commands, and to respond to questions.
- Exclusion criteria for SCI participants:
- Does not meet the inclusion criteria.
- Individuals with SCI
- Inclusion criteria:
- Age 16-65
- Injuries at the C3-6 level, complete (ASIA A), or incomplete (ASIA B and C).
- Able to follow simple commands
- Able to speak or respond to questions
You may not qualify if…
- Presence of tremors, spasm and other significant involuntary movements
- Cognitive impairment
- Deficit of visuo-spatial orientation
- Concurrent pressure sores or urinary tract infection
- Other uncontrolled infection, concurrent cardiovascular disease
- Sitting tolerance less than one hour
- Severe hearing or visual deficiency
- Miss more than six appointments without notification
- Unable to comply with any of the procedures in the protocol
- Unable to provide informed consent
- Stroke survivors:
- Inclusion criteria:
- Recent stroke (Sub acute to early chronic, between 3 and 12 months from CVA)
- Age less than 75 (To avoid age-related confounds)
- Inability to operate a manual wheelchair
- Available medical records and radiographic information about lesion locations
- Significant level of hemiparesis (UE Fugl Meyer score between 10 and 30)
- Presence of pathological muscle synergies in the UE (flexor and/or extensor synergy)
- Exclusion criteria:
- Aphasia, apraxia, cognitive impairment or affective dysfunction that would influence the ability to perform the experiment
- Inability to provide informed consent
- Severe spasticity, contracture, shoulder subluxation, or UE pain
- Severe current medical problems, including rheumatoid arthritis or other orthopaedic impairments restricting finger or wrist movement
- Additional exclusion criteria for participants enrolled in TMS procedures
- Any metal in head with the exception of dental work or any ferromagnetic metal elsewhere in the body. This applies to all metallic hardware such as cochlear implants, or an Internal Pulse Generator or medication pumps, implanted brain electrodes, and peacemaker.
Where it is running
- Shirley Ryan Ability Lab — Chicago, Illinois, United States (enrolling)
Full record on ClinicalTrials.gov
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