A Study of AZD8233 in Participants With Dyslipidemia

Completed · Phase 2 · Has a placebo group

Conditions studied: Dyslipidaemia

In brief

AZD8233 is a PCSK9-targeted ASO for the reduction of circulating levels of LDL-C. This study aims to evaluate the dose-dependent reduction in LDL-C after SC administration of multiple doses of AZD8233 as well as the associated adverse effects profile. The data generated will be used to guide choice of doses, dosing regimens, and sample sizes, as well as safety and PD monitoring in the further clinical development program.

Key facts

Study ID
NCT04641299
Run by
AstraZeneca
People needed
119
Starts
2020-10-28
Expected to finish
2021-07-20
Last updated by the study team
2022-11-18

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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