Pelvic Floor Dysfunction and Quality of Life in Uterine Cancer Survivors

Running, not enrolling

Conditions studied: Endometrial Carcinoma, Malignant Uterine Neoplasm, Uterine Corpus Cancer, Uterine Corpus Sarcoma

In brief

This trial studies pelvic floor dysfunction and quality of life in uterine cancer survivors. Using questionnaires may help researchers learn more about the sexual function and quality of life in uterine cancer survivors.

Key facts

Study ID

NCT04634617

Run by

M.D. Anderson Cancer Center

People needed

310

Starts

2020-01-09

Expected to finish

2027-04-11

Last updated by the study team

2026-05-20

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Patients with uterine cancer (including endometrial and uterine carcinoma or sarcoma) treated with surgery +/- radiation at MD Anderson between 2006 and 2017
• Eligible surgeries include laparoscopic or robotic assisted abdominal total hysterectomy, total abdominal hysterectomy, and vaginal hysterectomy with or without pelvic node dissection, with or without omentectomy or omental biopsies
• In addition, patients must have had all WITH bilateral-salpingo-oophorectomy (BSO), either during their surgery or in a previous or subsequent (within 3 months of endometrial cancer diagnosis) surgery
• Patients have had at least one year of follow-up
• Patients have not had any recurrence of disease
• Patients must be able to complete the survey of their own volition
• Patients must be able to read and speak English fluently
• CONTROL GROUP: Patients have never been diagnosed with any cancer other than non-melanomatous skin cancers
• CONTROL GROUP: Patient has undergone hysterectomy/BSO for benign reasons between 2006 and 2017
• CONTROL GROUP: Patients must be able to complete the survey of their own volition
• CONTROL GROUP: Patients must be able to speak and read English fluently

You may not qualify if…

• Patients with cancer recurrence, as this will affect their current quality of life
• Patients with additional pelvic surgery at the time of their hysterectomy (for example pelvic exenteration, urostomy placement, etc.)
• Patients with a secondary primary cancer (including cervical cancer), as this will affect their current quality of life. Patients may have either squamous cell or basal cell carcinoma of the skin
• Neurocognitive deficits that render patients unable to complete the survey on their own
• Patients who have not yet had removal of their bilateral ovaries
• Preoperative radiotherapy prior to hysterectomy

Where it is running

• M D Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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