Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment
Completed · Phase 2
Conditions studied: Smoking Cessation, Cancer, Treatment-Related
In brief
Smoking cessation has been shown to improve the effectiveness and reduce the morbidity of tobacco-related cancer treatments. We will identify effective smoking cessation strategies for patients who are receiving treatment for tobacco-related cancer. In this trial, patients' preferences in smoking cessation therapy will be the principal determinant by providers in developing a three component regimen of pharmaceutical therapy, counseling, and nicotine replacement therapy. This study will identify this cohort's preferences for smoking cessation strategies. We will then examine the impact of utilizing patient preferences upon cessation efficacy by directly comparing cessation success in this study with our recently completed study of the same population using the same tobacco treatments which were randomly assigned.
Key facts
- Study ID
- NCT04634071
- Run by
- Joseph Valentino, MD
- People needed
- 126
- Starts
- 2021-01-12
- Expected to finish
- 2026-01-02
- Last updated by the study team
- 2026-02-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- newly diagnosed or recurrent tobacco related malignancy
- smoked at least 1 cigarette within 4 weeks of study enrollment
- 10-pack year history of cigarette smoking
- smoked at least 1 cigarette within 1 month of cancer diagnosis
- life expectancy greater than 1 year
You may not qualify if…
- allergy to buproprion, varenicline and transdermal medicine
- history of suicide attempt
- hospitalized for psychiatric illness within past 2 years
- history of active or uncontrolled eating disorder
- uncontrolled epilepsy or seizure disorder
- pregnant or lactating
- within 3 months of myocardial infarction
- unstable angina
- uncontrolled hypertension
- serious arrhythmia
- history of taking varenicline or buproprion within one month of enrollment
- concurrent enrollment in tobacco cessation therapy
Where it is running
- Med Center Health — Bowling Green, Kentucky, United States
- University Of Kentucky, Markey Cancer Center — Lexington, Kentucky, United States
- Owensboro Health Mitchell Memorial Cancer Center — Owensboro, Kentucky, United States
Full record on ClinicalTrials.gov
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