Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria in Saliva and Bioaerosol Contamination
Completed · Phase 2 · Has a placebo group
Conditions studied: Healthy
In brief
To evaluate the anti-bacterial, pre-procedural, clinical efficacy of Peroxyl mouthwash (1.5% hydrogen peroxide) in saliva and the reduction of bioaerosol contamination as compared to a matching placebo mouthwash (0.0% hydrogen peroxide)
Key facts
- Study ID
- NCT04626778
- Run by
- Colgate Palmolive
- People needed
- 100
- Starts
- 2020-10-08
- Expected to finish
- 2020-12-15
- Last updated by the study team
- 2021-01-20
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Potential subjects must meet ALL of the following criteria:
- Subjects, ages 18-70, inclusive.
- Availability for the duration of this clinical research study.
- Good general health.
- At least 20 natural teeth.
- Gingivitis Index 1.0 (Löe-Silness).
- Signed Informed Consent Form
You may not qualify if…
- Potential subjects must NOT HAVE ANY of the following conditions:
- Symptoms consistent with COVID-19 or have tested positive.
- Presence of orthodontic bands.
- Tumor(s) of the soft or hard tissues of the oral cavity.
- Advanced periodontal disease (purulent exudate, tooth mobility, and/or extensive loss of periodontal attachment or alveolar bone) or peri-implantitis.
- Five or more carious lesions requiring immediate restorative treatment.
- Use of antibiotic one-month prior to entry into the study.
- Participation in any other clinical study or test panel within the one month prior to entry into the study.
- Dental prophylaxis during the past two weeks prior to baseline examinations.
- History of allergies to oral care/personal care consumer products or their ingredients.
- On any prescription medicines that might interfere with the study outcome.
- An existing medical condition that prohibits not eating or drinking for periods up to 4 hours.
- History of alcohol or drug abuse.
- Self-reported pregnant or lactating subjects.
Where it is running
- Loma Linda University School of Dentistry, Center for Dental Research — Loma Linda, California, United States
Full record on ClinicalTrials.gov
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