Neurobiology of Anorexia and Bulimia Nervosa

Completed · Not applicable

Conditions studied: Anorexia Nervosa, Bulimia Nervosa

In brief

The purpose of this study is to investigate areas of the brain responsible for appetite regulation. More specifically, the investigators would like to study changes in brain activation, e.g., changes in blood flow and oxygen use of the brain, during two different states: Once when the participants are hungry, and once when the participants are not hungry. The aim is to find out more about the neurobiology of Anorexia and Bulimia Nervosa by comparing women who never had an eating disorder with women who have recovered from Anorexia or Bulimia Nervosa.

Key facts

Study ID

NCT04626219

Run by

University of California, San Diego

People needed

150

Starts

2009-02-01

Expected to finish

2014-03-01

Last updated by the study team

2020-11-12

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Must have had a DSM-IV diagnosis of anorexia or bulimia nervosa
• The onset of their illness must have been at least 4 years prior to participating in this study
• Must have recovered for 12 months or more prior to entering the study.

You may not qualify if…

• Met diagnosis of alcohol or drug abuse or dependence in the 3 months prior to the study.
• Current diagnosis of a severe major affective or anxiety disorder or presence of other psychopathology that might interfere with ability to participate in the study.
• Organic brain syndromes, dementia, psychotic disorders or mental retardation
• Neurological or medical disorders
• Use of psychoactive medication in the 3 months prior to the study.
• Pregnancy or lactation, lack of effective birth control during 15 days before the scans.

Where it is running

• UCSD General Clinical Research Center — San Diego, California, United States

Full record on ClinicalTrials.gov

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