The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
Recruiting now
Conditions studied: Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Stage I Colorectal Cancer, Stage II Colorectal Cancer, Stage III Colorectal Cancer
In brief
The purpose of this research study is to determine whether testing of stool for a panel of markers will enable us to detect polyps and cancer compared to standard testing.
Key facts
- Study ID
- NCT04624555
- Run by
- Case Comprehensive Cancer Center
- People needed
- 50
- Starts
- 2022-10-31
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-04-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of stage I, II or III adenocarcinoma of the colon or rectum
- Receipt of preoperative colonoscopy
- Receipt of bowel resection; use of adjuvant chemotherapy or radiation therapy as clinically indicated
You may not qualify if…
- Stage IV colorectal cancer
- Surgical treatment with subtotal colectomy or total proctocolectomy
- Diagnosis of inflammatory bowel disease (ulcerative colitis or Crohn's disease)
- Diagnosis of polyposis syndrome including Lynch syndrome or familial polyposis
- Presence of advanced adenomas (1 cm or larger, villous features and/or high grade dysplasia) that were not removed at the preoperative colonoscopy or contained in the resection specimen.
- Inability to provide informed consent
- Inability to understand spoken and written English
- Medical comorbidities that would be contraindications to sedation or that would preclude any benefit of routine surveillance post-resection. These would be at the discretion of the participant's providers.
Where it is running
- University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center — Cleveland, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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