The Role of Hypoxia on Subconcussive Head Impacts

Completed · Not applicable

Conditions studied: Trauma, Brain

In brief

The purpose of this study is to examine the combined effects of hypoxia and a short bout of subconcussive head impacts on neurocognitive and ocular-motor function and plasma expression of brain-derived blood biomarkers.

Key facts

Study ID

NCT04624152

Run by

Indiana University

People needed

10

Starts

2018-10-22

Expected to finish

2019-05-01

Last updated by the study team

2020-11-10

Who can join

Age: 18 and older, up to 26. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Between 18 and 26 years old
• Current or former soccer player (i.e., collegiate, intramural, club, professional)
• At least 3 years of soccer heading experience
• Participants can read and speak English
• Participants have cell phone or computer with internet access to schedule for follow-up visits via email or text message
• Participant is willing to refrain from participating in any sport activity that purposefully uses one's head to maneuver (American football, ice-hockey, rugby, wrestling, and soccer heading) during study participation

You may not qualify if…

• Any head, neck, or face injury in the 1 year prior to the study (e.g., concussion, eye injury)
• History of vestibular, ocular, or vision dysfunction (e.g., macular degeneration)
• Currently taking any medications that trigger drowsiness
• Pregnancy
• Any history of neurological disorders (e.g., seizure disorders, closed head injuries with loss of consciousness greater than 15 minutes, CNS neoplasm, spinal cord injury/surgery, history of stroke)
• Lower extremity injury that would prohibit normal walking
• Metal implants in the head
• Conditional Exclusion Criteria
• Based on participants' self report: those who meet any of the following criteria, he/she will be either excluded or rescheduled (if they still wish to participate in the study):
• Slept less than 4 hours during the night prior to the testing day
• Consumed more than 3 alcoholic drinks within 24h prior to testing
• Used recreational drugs 24h prior to the testing day
• Consumed more than 300 mg of caffeine (the equivalent of about 3 cups of coffee) within 1h before testing sessions

Where it is running

• Indiana University — Bloomington, Indiana, United States

Full record on ClinicalTrials.gov

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