HelpILO - RCT on EILO Treatment

Recruiting now · Not applicable

Conditions studied: Exercise Induced Laryngeal Obstruction (EILO)

In brief

Exercise induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by continuous visualization of the larynx during high intensity exercise.

Key facts

Study ID

NCT04620343

Run by

Haukeland University Hospital

People needed

350

Starts

2021-01-01

Expected to finish

2036-12-31

Last updated by the study team

2022-08-16

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• EILO with CLE score at peak exercise graded as ≥ 2 at glottic or supraglottic level and
• Respiratory complaints to an extent that the patient wants further treatment and follow-up.

You may not qualify if…

• Breathing problems caused by disorders other than EILO or well controlled asthma.
• Perceived to be unable to perform repeated maximal cardiopulmonary treadmill exercise tests, or failing to accept the procedures required for repeated successful CLE tests, or unable to perform any of the other examinations required by the protocol.
• Abnormal anatomy at rest in the laryngeal region or the upper airways.
• Age below 12 years

Where it is running

• Haukeland University Hospital, Children and Youth Clinic — Bergen, Vestland, Norway (enrolling)

Full record on ClinicalTrials.gov

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