Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech

Recruiting now · Not applicable

Conditions studied: Aphasia, Apraxia of Speech, Dysarthria

In brief

The present study aims to investigate the short- and long-term effects of two weeks of intensive speech-language pathology intervention with additional physiotherapy, on aphasia and apraxia of speech (AOS) and their neural correlates in thirty persons with chronic stroke. Changes are studied following intensive treatment of aphasia and AOS with standardised speech-language testing and testing of communication and with voxel-based morphometry (VBM) analysis and resting state functional connectivity (rsFC).

Key facts

Study ID

NCT04604444

Run by

Karolinska Institutet

People needed

30

Starts

2017-02-02

Expected to finish

2027-12-31

Last updated by the study team

2024-10-31

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aphasia 7 months post stroke diagnosed by SLP
• Apraxia of Speech 7 months post stroke diagnosed by SLP

You may not qualify if…

• Dementia
• Severe loss of sight
• Severe loss of hearing
• Metal implants (preventing fMRI)
• Claustrophobia (preventing fMRI)

Where it is running

• Uppsala Universitet — Uppsala, Sweden (enrolling)

Full record on ClinicalTrials.gov

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