Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19
Status unconfirmed · Phase 4
Conditions studied: COVID-19
In brief
Researchers know that the virus that causes COVID-19 has been found in the saliva (spit) of individuals who exhibit signs of the disease. Investigators would like to test the ability of three mouthwashes to reduce the levels of this virus in participants' mouths. Investigators will ask participants to use a liquid to swish around in the mouth for 30 seconds and spit it into a collection cup. Investigators will also collect spit from participants before and after participants use the mouthwash. Although participants will have no direct benefits from the study, investigators will gain a wealth of information that would benefit patients who are at risk for COVID-19.
Key facts
- Study ID
- NCT04603794
- Run by
- Ohio State University
- People needed
- 60
- Starts
- 2020-10-01
- Expected to finish
- 2020-11-01
- Last updated by the study team
- 2020-10-27
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- adults age 18-80 admitted to The Ohio State University Medical Center,
- diagnosis of COVID-19 confirmed by Polymerase Chain Reaction (PCR),
- salivary carriage of COVID-19 virus
- ability to perform mouthwash rinses and to expectorate.
You may not qualify if…
- allergy to any study mouth rinse,
- active uncontrolled thyroid disease,
- pregnancy
- patients undergoing radioactive iodine therapy.
Where it is running
- The Ohio State University Wexner Medical Center — Columbus, Ohio, United States (enrolling)
Full record on ClinicalTrials.gov
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