Liposomal Bupivacaine vs Bupivacaine for Pain Control After Sternotomy

Status unconfirmed · Phase 1

Conditions studied: Pain Management, Sternotomy

In brief

Researchers hope to learn whether giving the longer-acting local anesthetic liposomal bupivacaine prior to closing the sternum is more effective in managing pain following sternotomy, than in patients who received standard bupivacaine before sternal closure. Researchers will measure this based on how much IV pain medication is used, rates on confusion, and time to remove the breathing tube.

Key facts

Study ID

NCT04585867

Run by

University of Kansas Medical Center

People needed

80

Starts

2017-10-11

Expected to finish

2023-10-10

Last updated by the study team

2020-10-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults over the age of 18 who present for elective open heart surgery that requires a sternotomy.

You may not qualify if…

• Urgent and emergency procedures,
• preexisting sternal infections,
• prior sternotomy,
• preexisting pain syndromes,
• current chronic home opioid use,
• anterior rib or sternal masses,
• allergy to any of the components of liposomal bupivacaine and plain bupivacaine.

Where it is running

• University of Kansas Medical Center — Kansas City, Kansas, United States (enrolling)

Full record on ClinicalTrials.gov

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