Stimulant Medication Effects on Auditory Sensitivity in Teens With ADHD

Completed

Conditions studied: Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, Attention Deficit Disorder With Hyperactivity

In brief

The aims of this study are to evaluate auditory sensitivity in teenagers with ADHD using acoustic reflex thresholds (ART) and to examine the effects of ADHD stimulant medication on ART.

Key facts

Study ID

NCT04577417

Run by

Nemours Children's Clinic

People needed

70

Starts

2020-09-13

Expected to finish

2022-06-15

Last updated by the study team

2022-12-13

Who can join

Age: 13 and older, up to 19. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Inclusion criteria for all:
• Participant must be aged 13 to 19 years
• Males and females
• All ethnicities
• All socioeconomic statuses
• Normal hearing
• English as a primary language
• Additional inclusion criteria for ADHD group:
• Participants must meet diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD), all subtypes, based on the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)
• Stimulant medication with the same drug and dosage for at least 1 year before their enrollment date

You may not qualify if…

• History of any major neurological disorders (e.g. seizures excluding febrile seizure under age 6 years, tumors, brain injury, cerebral palsy, tic disorders)
• History of any other major neuropsychiatric disorders (e.g. autism spectrum disorder, mood dysregulation),
• Presence of pressure equalization tubes in either ear
• Documented hearing impairment 20 decibel or higher hearing loss in either ear
• Estimated low cognitive function based on the NIH Toolbox Cognition age-corrected scores (<70)
• Additional exclusion criteria for the ADHD group
• Treatment with any psychotropic medications other than stimulants
• Treatment with any ADHD medication other than stimulants (e.g. alpha-agonists, norepinephrine reuptake inhibitors)
• Additional exclusion criteria for the control group
• Treatment with any psychotropic medication

Where it is running

• Nemours Children's Health — Wilmington, Delaware, United States

Full record on ClinicalTrials.gov

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