A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome
Stopped early · Phase 3 · Has a placebo group
Conditions studied: Epilepsies, Myoclonic
In brief
The primary purpose of the study is to demonstrate that lorcaserin has superior efficacy compared to placebo on percent change in frequency of convulsive seizures per 28 days in participants with Dravet syndrome.
Key facts
- Study ID
- NCT04572243
- Run by
- Eisai Inc.
- People needed
- 22
- Starts
- 2020-09-23
- Expected to finish
- 2024-08-15
- Last updated by the study team
- 2025-10-08
Who can join
Age: 2 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Children's of Alabama / University of Alabama at Birmingham — Birmingham, Alabama, United States
- University of California Los Angeles (UCLA) — Los Angeles, California, United States
- UCSD Rady's Children's Hosptial — San Diego, California, United States
- Children's Hospital Colorado — Aurora, Colorado, United States
- Northwest Florida Clinical Research Group — Gulf Breeze, Florida, United States
- Joe DiMaggio Children's Hospital — Hollywood, Florida, United States
- Miami Children's Hospital - Nicklaus Children's Hospital — Miami, Florida, United States
- Pediatric Neurology, P.A. — Winter Park, Florida, United States
- Rare Disease Research Center Pediatrics, LLC — Atlanta, Georgia, United States
- Mid-Atlantic Epilepsy and Sleep Center - Bethesda — Bethesda, Maryland, United States
- Spectrum Health/ Helen DeVos Children's Hospital — Grand Rapids, Michigan, United States
- University of Missouri, Department of Child Health, Division of Neurology — Columbia, Missouri, United States
- Institute of Neurology and Neurosurgery at Saint Barnabas — Livingston, New Jersey, United States
- Northwell Health - Neuroscience Institute at Great Neck — New Hyde Park, New York, United States
- NYU Langone Comprehensive Epilepsy Center — New York, New York, United States
- New York Medical College — New York, New York, United States
- NorthWell Health - Lennox Hill Hospital — New York, New York, United States
- University of Rochester Medical Center — Rochester, New York, United States
- University of North Carolina — Chapel Hill, North Carolina, United States
- Duke University Hospital Center — Durham, North Carolina, United States
- University Hospitals Cleveland Medical Center — Cleveland, Ohio, United States
- Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania, United States
- The University of Texas Health Science Center at Houston — Houston, Texas, United States
- Seattle Children's Hospital — Seattle, Washington, United States
- MultiCare Institute for Research & Innovation — Tacoma, Washington, United States
Full record on ClinicalTrials.gov
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