Mild Hypothermia for COVID-19 ARDS

Withdrawn before enrolling · Not applicable

Conditions studied: COVID19 ARDS

In brief

Some patients with COVID have abnormally high carbon dioxide and low oxygen levels despite being on the ventilator. The hypothesis of the study is that the application of mild hypothermia to patients with COVID will decrease their metabolic rate and improve their oxygenation and carbon dioxide levels.

Key facts

Study ID

NCT04570462

Run by

Northwell Health

People needed

0

Starts

2020-05-18

Expected to finish

2020-12-31

Last updated by the study team

2021-06-29

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Provision of signed and dated informed consent form from Legally Authorized Representative.
• Stated willingness to comply with all study procedures and availability for the duration of the study
• Male or female, aged 18 years or above
• COVID positive
• On mechanical ventilation with either: refractory respiratory acidosis (ph ≤ 7.20), hypercarbia (pCO2 ≥ 55 mmHg), refractory hypoxia (pO2/FIO2 <150), or plateau pressures >30

You may not qualify if…

• Bleeding (active bleeding, platelets less than 50,000)
• Uncontrolled cardiac arrhythmia
• History of cryoglobulinemia, major trauma, pregnancy
• Active non-COVID-19 infection that is not controlled with antibiotic or antifungal regimen

Where it is running

• North Shore University Hospital — Manhasset, New York, United States

Full record on ClinicalTrials.gov

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