Scleral Lens Fitting Using Wide-Field OCT

Recruiting now

Conditions studied: Keratoconus, Irregular; Contour of Cornea

In brief

The purpose of this study is to see if OCT technology can optimize scleral contact lens fittings. Subjects with keratoconus, post-penetrating keratoplasty (PK), post-LASIK ectasia, post-radial keratotomy (RK), or a variety of anterior surface disorders requiring scleral lens fittings will be considered for enrollment. For each study eye, a clinically-selected scleral lens fit will be compared against an OCT-selected lens fit. The quality of each lens fit will be determined by flourescein exam at the slit lamp. Apical clearance, limbal clearance, conjunctival compression, and lens edge lift will be assessed. A lens that satisfies all four criteria will be considered satisfactory.

Key facts

Study ID

NCT04570020

Run by

Oregon Health and Science University

People needed

258

Starts

2020-09-23

Expected to finish

2028-12-01

Last updated by the study team

2025-09-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eyes requiring fit for scleral lenses for KCN, post-PK, post-RK, post-LASIK ectasia, or various anterior surface disorders

You may not qualify if…

• Inability to maintain stable fixation for OCT imaging
• Inability to commit to required visits to complete the study
• Eyes with concurrent retinal diseases, glaucoma, or other eye conditions that may limit visual outcome

Where it is running

• Oregon Health & Science University, Casey Eye Institute — Portland, Oregon, United States (enrolling)

Full record on ClinicalTrials.gov

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