Sleep Spindles and Memory in Rolandic Epilepsy

Withdrawn before enrolling · Not applicable

Conditions studied: Rolandic Epilepsy, Rolandic Epilepsy, Benign, Centrotemporal Epilepsy, Centrotemporal; EEG Spikes, Epilepsy of Childhood, Epilepsy; Seizure, Epilepsy

In brief

The investigators are recruiting children with Rolandic epilepsy and children without epilepsy (aged 4 years old and above) for a non-invasive brain imaging study using Magnetic Resonance Imaging (MRI), Magnetoencephalography/Electroencephalography (MEG/EEG), and experimental tasks. The investigators hope to determine the brain circuits and brain rhythms affected in these children and ultimately identify new treatment options for childhood epilepsy patients.

Key facts

Study ID

NCT04569708

Run by

Massachusetts General Hospital

People needed

0

Starts

2021-01-16

Expected to finish

2025-06-30

Last updated by the study team

2026-08-07

Who can join

Age: 4 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of childhood epilepsy with centrotemporal spikes (CECTS)or Rolandic epilepsy by child neurologist
• Ages 4-18 years
• Has an EEG with sleep activated centrotemporal spikes
• Has had at least 1 focal motor or generalized seizure

You may not qualify if…

• Has abnormal brain MRI
• Has other unrelated neurological disease
• Unable to have an MRI/MEG due to claustrophobia, history of frequent vomiting, permanent metal in body (braces), or over MRI weight limit: 350lbs

Where it is running

• Athinoula A. Martinos Center Biomedical Imaging — Charlestown, Massachusetts, United States

Full record on ClinicalTrials.gov

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