Relationships Between Vitamin D and Orthopedic Trauma

Completed

Conditions studied: Fracture, Fracture Nonunion, Fractures, Bone, Vitamin D

In brief

Vitamin D is an essential hormone involved in bone metabolism, bone mineral density maintenance, and bone health. Vitamin D deficiency is putatively linked to poor pediatric orthopedic outcomes \[1\]. Further, the risk of low vitamin D associated fractures may be greater in minority pediatric populations \[2\]. In adults, utility of vitamin D alleles as a biomarker for bone density and fracture risk has been debated for over 10 years \[3-5\]. Peak bone density is achieved at 25 years old; however, most orthopedic trauma patients less than 25 years of age present with substantial vitamin D deficiencies.

Key facts

Study ID

NCT04564625

Run by

Methodist Health System

People needed

100

Starts

2020-03-06

Expected to finish

2021-02-26

Last updated by the study team

2026-05-19

Who can join

Age: 18 and older, up to 25. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients must be >18 years old and ≤25 years old
• Patients must have any fracture requiring follow-up
• Patients must have received vitamin-D assessment

You may not qualify if…

• Patients aged >25yrs
• Prisoners
• Pregnant

Where it is running

• Methodist Health System Clinical Research Institute — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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