Locomotor Learning in Infants at High Risk for Cerebral Palsy
Completed · Not applicable
Conditions studied: Cerebral Palsy
In brief
The objective of this project is to characterize the evolution of locomotor learning over the first 18 months of life in infants at high risk for cerebral palsy (CP). To characterize how locomotor skill is learned (or not learned) during this critical period, the investigators will combine established protocols using robust, unbiased robotic and sensor technology to longitudinally study infant movement across three consecutive stages during the development of impaired human motor control - early spontaneous movement, prone locomotion (crawling), and upright locomotion (walking).
Key facts
- Study ID
- NCT04561232
- Run by
- Children's Hospital of Philadelphia
- People needed
- 60
- Starts
- 2020-12-15
- Expected to finish
- 2025-08-04
- Last updated by the study team
- 2026-06-29
Who can join
Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- less than 6 weeks of age (corrected for prematurity, if applicable)
- have a history of an early brain injury associated with high risk for cerebral palsy including periventricular leukomalacia, hypoxic-ischemic encephalopathy, intraventricular hemorrhage, hydrocephalus, stroke, neonatal seizures, or intracranial cystic lesion
- family is able to commit to study visits
You may not qualify if…
- known genetic condition unrelated to cerebral palsy (CP) or congenital abnormalities
- Infants with fidgety movements on the General Movements Assessments (GMA) at 3 months of age or a score greater than -0.5sd below the mean on the Test of Infant Motor Performance at 4 months of age will not progress in the study because these infants are unlikely to have CP.
Where it is running
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.