Pilot Studies Testing Levels of P63 in Psoriasis Skin Lesions
Completed
Conditions studied: Psoriasis
In brief
The purpose of this study is to understand the role of a specific protein, tumor protein p63 in the skin disease psoriasis. This study is to further understand how psoriasis lesions happens. An understanding of key mediators that lead to psoriasis might aid in the discovery of more effective treatments for this skin disorder. This is not an intervention study. The study is looking to obtain currently untreated plaque psoriasis biopsies and also biopsies from non psoriasis patients. Psoriasis and medical history will be collected then skin biopsies will be obtained from the subjects.
Key facts
- Study ID
- NCT04560647
- Run by
- Wright State University
- People needed
- 9
- Starts
- 2020-12-03
- Expected to finish
- 2023-04-14
- Last updated by the study team
- 2023-04-21
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Female and Male adult subjects age 18 to 50 with plaque psoriasis that is currently untreated (no topical agents for 2 weeks, no systemic agents for 1 month) or controls w/o psoriasis and no family history of psoriasis.
- Must be able to give informed consent
- All skin types on Fitzpatrick Scale (Type I-VI)
- Able to provide medical history and list of medications for psoriasis and control subjects
You may not qualify if…
- Underlying diseases that could affect wound healing (e.g., uncontrolled diabetes mellitus)
- Tanning bed use within last 2 months
- Photodynamic Therapy or UVB treatments in past 2 months
- Female Subjects: pregnant or nursing
- History of abnormal scarring (i.e., keloids)
- Family history of psoriasis in first-degree relatives for control subjects
Where it is running
- Wright State Physicians — Fairborn, Ohio, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.