Comparing Fluoride Varnish and Sealant to Prevent White Spots in Orthodontic Patients

Completed · Not applicable

Conditions studied: White Spot Lesion

In brief

The purpose of the study is o compare the efficacy of CPP-ACP MI Varnish and ProSeal sealant in preventing white spot lesion (WSL) formation in orthodontic patients.

Key facts

Study ID

NCT04560478

Run by

Texas A&M University

People needed

40

Starts

2018-10-01

Expected to finish

2020-03-01

Last updated by the study team

2020-09-23

Who can join

Age: 12 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• no significant medical history
• no underlying medical problems such as Sjogren's Syndrome or conditions requiring more than 2 medications (to prevent bias of possible dry mouth)
• less than 17 years old at the start of orthodontic treatment,
• fully erupted permanent maxillary canines and incisors, starting fixed orthodontic treatment
• ability to come to appointments every 4-6 weeks.

You may not qualify if…

• professional fluoride application in the last 3 months
• allergy to milk
• untreated cavitated lesions
• heavy initial fluorosis
• dry mouth
• pregnancy
• any illness/condition that the investigators felt would affect the study outcome.

Where it is running

• Texas A&M University College of Dentistry — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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