Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Postoperative Wound Haemorrhage

In brief

Bleeding after Mohs micrographic surgery for skin cancer is a low risk complication that can occur. This study aims to determine the effect of a drug, often used to reduce bleeding, called tranexamic acid when applied topically to the skin wound after surgery.

Key facts

Study ID

NCT04541303

Run by

University of Missouri-Columbia

People needed

124

Starts

2020-10-08

Expected to finish

2021-12-30

Last updated by the study team

2024-11-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All adult (18 years or older) patients presenting for Mohs micrographic surgery (MMS) for the treatment of melanoma or nonmelanoma skin cancer (NMSC) with a wound that will be healing by granulation

You may not qualify if…

• Patients must not be pregnant or breastfeeding.
• Patients must not have a known allergic reaction or sensitivity to TXA
• Patient must not have an international normalized ratio (INR) out of therapeutic range if on warfarin.

Where it is running

• University of Missouri-Columbia — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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