Intraoperative Brain Microdialysis to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection.

Withdrawn before enrolling · Not applicable

Conditions studied: Epilepsy

In brief

This research study will investigate the fluid from the area of the brain that is being removed during clinical epilepsy surgery. The goal is to analyze this fluid for inflammatory markers that can potentially help identify new strategies in the future to control seizures in individuals with epilepsy who fail to respond to currently available drugs.

Key facts

Study ID

NCT04531722

Run by

Mayo Clinic

People needed

0

Starts

2019-03-27

Expected to finish

2026-01-10

Last updated by the study team

2026-04-06

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Failure to respond to at least two trials of anti-seizure drugs with different mechanisms of action
• Normal MRI

You may not qualify if…

• Active immunomodulatory therapy
• Autoimmune disorder
• Signs or symptoms consistent with comorbid infection
• Oncological comorbidity

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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