The Effect of Melatonin and Vitamin C on COVID-19

Completed · Not applicable · Has a placebo group

Conditions studied: Covid19, SARS-CoV Infection

In brief

This is a double-blind placebo controlled trial that seeks to evaluate the impact of melatonin and vitamin C on symptoms and outcomes of patients with COVID-19.

Key facts

Study ID

NCT04530539

Run by

Lancaster General Hospital

People needed

122

Starts

2020-10-05

Expected to finish

2022-08-11

Last updated by the study team

2022-08-17

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• COVID-19 positive test (outpatient testing),
• Age >50 (chosen based greater risk for older patients to be vitamin deficient, age >65 not used so as not to be too restrictive in the inclusion criteria)
• Experiencing symptoms for <5 days prior to enrollment
• Able to read and write in English or Spanish
• Able to access REDCap daily
• Valid email address
• Current has a Lancaster General Health primary care physician

You may not qualify if…

• COVID-19 test ordered pre-procedure for asymptomatic screening
• Currently taking vitamin C supplements
• Currently taking melatonin supplements
• Currently hospitalized
• Deceased
• Currently pregnant
• Currently incarcerated

Where it is running

• Lancaster General Health — Lancaster, Pennsylvania, United States

Full record on ClinicalTrials.gov

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