PRIMA Intervention for Adults With Mild Cognitive Impairment and Their Caregivers

Completed · Not applicable

Conditions studied: Mild Cognitive Impairment

In brief

The investigators developed and tested the Daily Engagement in Meaningful Activities (DEMA) intervention to improve life satisfaction and health outcomes for patients and caregivers. DEMA is a positive health focused, theoretically grounded, tailored, family-centered, multi-faceted intervention. Over 7 session, dyads work with a nurse to 1) identify meaningful activities, assess capacity, problem-solve barriers, and establish routines for engagement and 2) learn more about MCI by working through six Self-Management Toolkit topics (e.g., benefits of meaningful activity; planning the future). The investigators' purpose is to evaluate the efficacy of DEMA in a two-group randomized controlled trial with 210 patient/caregiver dyads (DEMA intervention vs. the information support (IS) attention control group).

Key facts

Study ID

NCT04515875

Run by

Indiana University

People needed

420

Starts

2021-12-13

Expected to finish

2025-07-20

Last updated by the study team

2026-07-15

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• a diagnosed untreated severe major depression, or receiving advanced cancer treatment or hospice care
• receiving dialysis
• severe hearing loss and no hearing aids
• have no access to a telephone
• the family caregiver has significant cognitive impairment that may hinder participation (6-item MMSE < 4).

Where it is running

• Indiana University Alzhemier Disease Research Center — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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