Adductor Canal Block

Stopped early · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Osteoarthritis, Total Knee Replacement

In brief

The investigators aim to investigate whether the addition of a surgeon-administered adductor canal blockade to a multimodal periarticular injection cocktail provides additional pain relief for patients undergoing total knee arthroplasty. This study will help identify the effectiveness of surgeon-administered adductor canal blockade in perioperative pain control for patients undergoing total knee arthroplasty

Key facts

Study ID: NCT04513145
Run by: OrthoCarolina Research Institute, Inc.
People needed: 93
Starts: 2020-10-09
Expected to finish: 2025-05-23
Last updated by the study team: 2026-04-06

Who can join

Age: 30 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Patients age 30-85undergoing first-time primary unilateral total knee arthroplasty for osteoarthritis and remaining hospitalized for at least one night

You may not qualify if…

Patients undergoing revision total knee arthroplasty
Patients undergoing bilateral total knee arthroplasty
Workers compensation patients
Patients undergoing total knee arthroplasty for post-traumatic arthritis
Patients with inflammatory arthritis
Patients with any previous surgery on the operative knee which involved an arthrotomy
Patients taking opioids prior to total knee arthroplasty
Patients with a known history of drug or alcohol abuse
Patients undergoing total knee arthroplasty at an ambulatory surgery center, or being discharged home from the hospital on the same day as their procedure (planned)
Patients who have had a total knee arthroplasty performed on the contralateral knee

Where it is running

OrthoCarolina Research Institute, OrthoCarolina, P.A. — Charlotte, North Carolina, United States

Full record on ClinicalTrials.gov

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