Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty

Recruiting now · Phase 4

Conditions studied: Arthroplasty, Replacement, Shoulder

In brief

The aim of the study is to evaluate if intravenous steroid supplementation can provide advantages over routine analgesia protocols in terms of post-operative symptoms (pain and nausea), length of hospital stay, shoulder range of motion, function and patient satisfaction

Key facts

Study ID

NCT04507412

Run by

Christian Candrian

People needed

74

Starts

2020-09-09

Expected to finish

2032-08-31

Last updated by the study team

2026-03-05

Who can join

Age: 58 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing unilateral primary total anatomical or reverse shoulder arthroplasty (Total Shoulder Arthroplasty)
• Patients with a BMI >18.5 and <35
• Patients able to provide informed consent and follow all the study procedures as indicated by the protocol
• Informed Consent as documented by signature

You may not qualify if…

• Contraindications to steroids
• Revision and post-traumatic TSA
• Active steroid or immunosuppressive therapy in the last 30 days before the operation
• Pregnant or breast-feeding women
• Presence of other clinically significant concomitant disease states (ASA IV)
• Uncontrolled diabetes mellitus
• Contraindications to Non-steroidal anti-inflammatory drugs
• Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus), gout, rheumatic arthritis
• Known or suspected non-compliance, drug or alcohol abuse
• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.
• Participation in another study with investigational drug within the 30 days preceding and during the present study
• Previous enrolment into the current study
• Enrolment of the investigator, his/her family members, employees and other dependent persons

Where it is running

• Christian Candrian — Lugano, Switzerland (enrolling)

Full record on ClinicalTrials.gov

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