Sensory-specific Peripheral Stimulation for Tremor Management
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Conditions studied: Parkinson's Disease, Essential Tremor
In brief
The purpose of this study is to understand the neurophysiological mechanisms of peripheral electrical stimulation (PES) in modulating supraspinal tremorogenic input to motoneurons. For this purpose, the investigators will use transcutaneous PES, high-density electromyography (HD-EMG), transcranial magnetic stimulation (TMS), electroencephalography (EEG), magnetic resonance imaging (MRI), and neuromusculoskeletal modelling. This study will be carried out in both healthy participants and patients with essential tremor (ET) and Parkinson's disease (PD).
Key facts
- Study ID
- NCT04501133
- Run by
- Shirley Ryan AbilityLab
- People needed
- 180
- Starts
- 2020-09-01
- Expected to finish
- 2026-07-15
- Last updated by the study team
- 2026-07-14
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
Where it is running
- Shirley Ryan AbilityLab — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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