Casting vs Bracing for Idiopathic Early-Onset Scoliosis

Running, not enrolling · Not applicable

Conditions studied: Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine

In brief

Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis

Key facts

Study ID

NCT04500041

Run by

University of Iowa

People needed

71

Starts

2021-02-09

Expected to finish

2026-09-30

Last updated by the study team

2026-03-13

Who can join

Age: 1 and older, up to 3. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient Inclusion
• Diagnosis of idiopathic early-onset scoliosis
• Child standing independently but not older than 3 years of age
• 20≤ Cobb angle ≤70° (largest structural curvature)
• Rib-vertebral angle difference (RVAD) greater than 20 degrees or Rib Phase II
• Parental consent to participate
• Parent Inclusion
• Parent or guardian of the minor subject
• Consent to participate
• Able to complete surveys

You may not qualify if…

• Patient Exclusion
• Previous operative or non-operative treatment for idiopathic early-onset scoliosis
• Not independently walking by 18 months of age or other signs/symptoms indicative of developmental delay

Where it is running

• Arkansas Children's Hospital — Little Rock, Arkansas, United States
• Children's Hospital Colorado — Aurora, Colorado, United States
• Nemours/Alfred I. duPont Hospital for Children — Wilmington, Delaware, United States
• Children's Healthcare of Atlanta — Atlanta, Georgia, United States
• Lurie Children's Hospital of Chicago — Chicago, Illinois, United States
• Shriners Hospitals for Children - Chicago — Chicago, Illinois, United States
• University of Iowa — Iowa City, Iowa, United States
• Johns Hopkins — Baltimore, Maryland, United States
• Children's Hospital of Boston — Boston, Massachusetts, United States
• University of Michigan — Ann Arbor, Michigan, United States
• Gillette Children's Specialty Healthcare — Saint Paul, Minnesota, United States
• Children's Mercy Kansas City — Kansas City, Missouri, United States
• St. Louis Children's Hospital/Washington University — St Louis, Missouri, United States
• Golisano Children's Hospital/University of Rochester — Rochester, New York, United States
• University of North Carolina Chapel Hill — Chapel Hill, North Carolina, United States
• Duke University Medical Center — Durham, North Carolina, United States
• Doernbecher Children's Hospital / OHSU — Portland, Oregon, United States
• Shriners Hospitals for Children - Portland — Portland, Oregon, United States
• Children's Hospital of Pennsylvania — Philadelphia, Pennsylvania, United States
• Shriners Hospitals for Children - Philadelphia — Philadelphia, Pennsylvania, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States
• Texas Children's Hospital — Houston, Texas, United States
• University of Virginia — Charlottesville, Virginia, United States
• Seattle Children's Hospital — Seattle, Washington, United States
• Italian Scientific Spine Institute (ISICO) — Milan, Italy

Full record on ClinicalTrials.gov

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