Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding

Recruiting now · Phase 2/Phase 3

Conditions studied: Esophageal Varices

In brief

Carvedilol versus endoscopic band ligation for primary prophylaxis of oesophageal variceal bleeding in cirrhotic patients with arterial hypertension

Key facts

Study ID

NCT04499898

Run by

Sherief Abd-Elsalam

People needed

306

Starts

2018-10-01

Expected to finish

2030-12-10

Last updated by the study team

2020-08-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• • Aged >18 years
• Cirrhotic patients with arterial hypertension
• Endoscopic evidence of medium/large-sized esophageal varices

You may not qualify if…

• • History of variceal bleeding or previous primary prevention of varices.
• Portal vein thrombosis or previous porto-systemic shunts as TIPS.
• Patients on drugs affecting portal pressure (beta blockers, nitrates).
• Advanced cardiovascular disease including acute myocardial infarction, atrio-ventricular block, congestive heart failure, chronic peripheral ischemia, severe bradycardia.
• Patients with severe respiratory diseases (COPD, bronchial asthma).
• Uncontrolled diabetes mellitus
• Renal impairment
• Hepatocellular carcinoma
• Allergy to carvedilol
• Pregnancy or lactation

Where it is running

• Sherief Abd-Elsalam — Tanta, Egypt (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.