Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of KPL-404 in Healthy Subjects

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy Volunteers

In brief

Phase 1, randomized, double-blind, placebo-controlled first-in-human study to investigate the safety, tolerability, PK and PD properties of single ascending intravenous (IV) and subcutaneous (SC) doses of KPL-404 in healthy subjects

Key facts

Study ID

NCT04497662

Run by

Kiniksa Pharmaceuticals, Ltd.

People needed

52

Starts

2019-10-22

Expected to finish

2021-03-02

Last updated by the study team

2021-05-04

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

Where it is running

• PPD Clinic — Austin, Texas, United States
• Q-Pharm Pty Ltd — Herston, Queensland, Australia

Full record on ClinicalTrials.gov

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