Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain

Completed · Not applicable · Has a placebo group

Conditions studied: Opioid Use, Marijuana, Chronic Pain

In brief

This study will examine how discounted vouchers for medical cannabis use affects opioid analgesic use in adults with chronic pain. Our study findings will have critically important implications to shape clinical care and medical cannabis policies.

Key facts

Study ID

NCT04495725

Run by

Vireo Health

People needed

270

Starts

2020-10-06

Expected to finish

2024-03-13

Last updated by the study team

2026-03-10

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• >18 years old
• English or Spanish fluency
• active certification for medical cannabis
• intends to have a soft-gel capsule product dispensed at Vireo Health
• medical cannabis qualifying conditions or complications of (a) chronic pain, or (b) pain that degrades health and functional capability as an alternative to opioid use or substance use disorder or (c) severe or chronic pain
• joint or neuropathic pain
• current severe pain
• dispensed opioids analgesics within the last 60 days
• To maintain the integrity of the study, we do not disclose all inclusion criteria to potential participants.

You may not qualify if…

• inability to provide informed consent
• inability to complete study visits over 14 weeks
• terminal illness
• current or prior psychotic disorder
• current or prior buprenorphine or methadone treatment for opioid use disorder
• NYS medical marijuana prescriber does not approve changes to product and dosing recommendations listed on the participant's certification form
• Allergy to tapioca or coconut
• currently pregnant, planning to become pregnant within the next 3 months, or breastfeeding
• a condition that is considered by a pharmacist or medical provider to be a clinical contraindication to medical cannabis use (e.g. unstable cardiac arrhythmia or specific drug-drug interaction)

Where it is running

• Vireo Health of New York — Queens, New York, United States

Full record on ClinicalTrials.gov

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