A Study of Ramucirumab (LY3009806) in Healthy Participants

Completed · Phase 1 · Has a placebo group

Conditions studied: Healthy

In brief

This study evaluates a new formulation of ramucirumab, a drug approved for several types of cancer. In this study of healthy participants, a small amount of ramucirumab will be given by injection either into a vein or just under the skin. Study doctors will measure the amount of ramucirumab in the bloodstream. Side effects and tolerability will be documented. The study will last for about 16 weeks for each participant, including screening and follow up. Screening is required within 28 days prior to entering the study.

Key facts

Study ID

NCT04495478

Run by

Eli Lilly and Company

People needed

50

Starts

2020-07-30

Expected to finish

2021-05-09

Last updated by the study team

2023-02-14

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Overtly healthy male or a female (not pregnant and agreeable to take birth control measures until study completion)
• Have a body weight greater than or equal to (≥)70 kilograms (kg) and body mass index (BMI) of 18 to 32 kilogram per square meter (kg/m ²), inclusive
• Have normal blood pressure, pulse rate, electrocardiogram (ECG), and blood and urine laboratory test results that are acceptable for the study

You may not qualify if…

• Are currently participating in or completed a clinical trial within the last 30 days or any other type of medical research judged to be incompatible with this study
• Have previously participated or withdrawn from this study
• Have or used to have health problems or laboratory test results or ECG readings that, in the opinion of the doctor, could make it unsafe to participate, or could interfere with understanding the results of the study
• Had blood loss of more than 500 milliliters (mL) within the previous 30 days of study screening

Where it is running

• Covance Clinical Research Inc — Daytona Beach, Florida, United States

Full record on ClinicalTrials.gov

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