A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
Recruiting now · Phase 1/Phase 2
Conditions studied: Endometrial Cancer
In brief
This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurrent and/or persistent endometrial cancer. The main protocol provides a platform for genomic screening with homogeneous basic eligibility criteria in order to direct study participants into biomarker-matched study cohorts consisting of testing targeted agents.
Key facts
- Study ID
- NCT04486352
- Run by
- Alliance Foundation Trials, LLC.
- People needed
- 148
- Starts
- 2021-10-20
- Expected to finish
- 2027-10-01
- Last updated by the study team
- 2026-04-01
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- University of Oklahoma Health Stephenson Cancer Center — Oklahoma City, Oklahoma, United States (enrolling)
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Medstar Georgetown Cancer Institute — Washington D.C., District of Columbia, United States
- Mount Sinai Comprehensive Cancer Center — Miami Beach, Florida, United States
- University of Chicago — Chicago, Illinois, United States
- University of Kansas Cancer Center — Westwood, Kansas, United States
- Maine Medical Center — Scarborough, Maine, United States
- Dana Farber Cancer Institute — Boston, Massachusetts, United States
- University of Minnesota — Minneapolis, Minnesota, United States
- Washington University School of Medicine Siteman Cancer Center — St Louis, Missouri, United States
- Nebraska Methodist Hospital — Omaha, Nebraska, United States
- Englewood Health — Englewood, New Jersey, United States
- Atlantic Health Systems/Morristown Medical Center — Morristown, New Jersey, United States
- Roswell Park — Buffalo, New York, United States
- Weill Cornell Medicine — New York, New York, United States
- Duke University Cancer Center — Durham, North Carolina, United States
- Providence Portland Cancer Institute — Portland, Oregon, United States
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States
- Lifespan - Rhode Island Hospital — Providence, Rhode Island, United States
- City of Hope Comprehensive Cancer Center — Duarte, California, United States
- Baptist Memorial Hospital — Memphis, Tennessee, United States
Full record on ClinicalTrials.gov
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