Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension

Recruiting now · Phase 4 · Has a placebo group

Conditions studied: Pulmonary Hypertension Due to Left Heart Disease

In brief

The investigator compared difference between inhaled and intravenous milirinone in patiens with severe pulmonary hypertension undergoing cardiac surgery

Key facts

Study ID

NCT04484675

Run by

Zagazig University

People needed

38

Starts

2023-05-20

Expected to finish

2025-05-10

Last updated by the study team

2025-04-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled to undergo mitral valve surgery by cardiopulmonary bypass with estimated mean pulmonary artery pressure =>55 estimated by using preoperative Doppler echocardiography

You may not qualify if…

• Patients were excluded if they had surgery without CPB, preoperative hemodynamic instability (defined as acute requirement for vasoactive support or mechanical device),Patients with severe LV dysfunction (LV ejection fraction of less than 30% congenital heart disease, a contraindication to transesophageal echocardiography (TEE), emergency surgery or re-do surgeries severe renal or hepatic disease
• , coagulopathy, and thromboembolic disease treated with anticoagulants

Where it is running

• Zagazig University — Zagazig, Sharqia Province, Egypt (enrolling)

Full record on ClinicalTrials.gov

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