Multidisciplinary Intervention In Chronic GVHD

Running, not enrolling · Not applicable

Conditions studied: Stem Cell Transplant Complications, Graft Vs Host Disease, Coping Skills, Quality of Life

In brief

This research is being done to evaluate the feasibility and efficacy of a multidisciplinary, patient-centered intervention, Horizons Program, versus minimally enhanced standard care to improve quality of life, symptom burden and psychological distress of adults who received an allogeneic hematopoietic stem cell transplant and developed graft versus-host disease (GVHD).

Key facts

Study ID

NCT04479995

Run by

Massachusetts General Hospital

People needed

80

Starts

2020-08-02

Expected to finish

2027-12-01

Last updated by the study team

2026-01-20

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adult patients (≥ 21 years) who underwent allogeneic HCT
• have moderate to severe chronic GVHD
• are currently receiving their care at the MGH Blood and Marrow Transplant Clinic
• have the ability to participate in an English language group intervention

You may not qualify if…

• Patients with comorbid conditions or cognitive impairment that the treating clinician believes prohibits informed consent or participation in the intervention
• Vulnerable patients, defined here as prisoners and pregnant women, will not be included in the intervention

Where it is running

• Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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