A Study to Evaluate the Effect of Fluconazole, Bupropion, or Itraconazole on the Drug Levels and Safety of BMS-986235

Withdrawn before enrolling · Phase 1

Conditions studied: Healthy Participants

In brief

This study will evaluate the effect of inhibitors, at steady state, on the drug levels, safety, and tolerability of BMS-986235 when taken by healthy participants. The inhibitors to be utilized in this study are fluconazole, bupropion, and itraconazole.

Key facts

Study ID

NCT04464577

Run by

Bristol-Myers Squibb

People needed

0

Starts

2021-04-01

Expected to finish

2021-06-08

Last updated by the study team

2022-03-25

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body mass index of 18.0 kg/m2 to 32.0 kg/m2, inclusive, at screening.
• Males and females must agree to follow specific methods of contraception, if applicable.
• Healthy participants, as determined by no clinically significant deviation from normal in physical examination, ECGs, and clinical laboratory determinations, and no significant findings in medical history.

You may not qualify if…

• Women of childbearing potential (WOCBP), women who are pregnant or breastfeeding
• Inability to tolerate oral medication
• Known previous exposure to BMS-986235.
• Other protocol-defined inclusion/exclusion criteria apply

Where it is running

• Local Institution — Lenexa, Kansas, United States
• Local Institution — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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