Electrical Synchronization of Slow Oscillations to Enhance Deep Sleep
Completed · Early Phase 1 · Has a placebo group
Conditions studied: Sleep, Sleep Hygiene
In brief
This study applied slowly oscillating (0.5 hz) transcranial electrical stimulation (TES; frontopolar and lateral frontal electrodes versus mastoid and occipital electrode returns) to synchronize the endogenous slow oscillations (SOs) of deep sleep (N3 or stage 3 Non-REM). A double-blind placebo control provided no stimulation. The primary endpoint was duration of N3 sleep during the night. Thirteen normal adults completed the study (before the study was terminated because of COVID-19), and usable data were obtained from ten. The synchronizing stimulation resulted in significantly longer N3 sleep compared to placebo.
Key facts
- Study ID
- NCT04461769
- Run by
- Brain Electrophysiology Laboratory Company
- People needed
- 13
- Starts
- 2019-09-01
- Expected to finish
- 2020-05-30
- Last updated by the study team
- 2020-07-08
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- history of seizures
- epilepsy
- brain trauma or injury
- insomnia
- sleep apnea
- medications that may affect the EEG.
Where it is running
- Brain Electrophysiology Laboratory Company — Eugene, Oregon, United States
Full record on ClinicalTrials.gov
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