Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

Status unconfirmed · Not applicable · Has a placebo group

Conditions studied: no Condition, Electroencephalography, Pupil Diameter

In brief

This study investigates the capacity of non-invasive vagus nerve stimulation, applied at the ear, to alter to measures of locus coeruleus output pupil diameter and EEG alpha power. Non-invasive alteration in locus coeruleus output is of interest in regard to basic science and has potential clinical implications in a number of conditions.

Key facts

Study ID

NCT04455295

Run by

Arkansas Tech University

People needed

55

Starts

2020-09-01

Expected to finish

2025-06-01

Last updated by the study team

2024-02-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy, 18 years of age or older.

You may not qualify if…

• self-report of mood disorders, prescription and non-prescription drug use which includes stimulants including caffeine and nicotine

Where it is running

• Arkansas Tech University — Russellville, Arkansas, United States

Full record on ClinicalTrials.gov

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