RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy

Recruiting now

Conditions studied: Epilepsy

In brief

Resting-state functional MRI (r-fMRI) has emerged in recent years to analyze resting networks. It allows, without active participation of the patients, to identify and analyze the different functional brain networks. The analysis of r-fMRI can be done thanks to the graph theory, which is based on the based on the calculation of quantifiable parameters applied to the functional network studied, making it possible to assess its effectiveness. To the knowledge of the investigators, no study has used graph theory applied to r-fMRI data in order to obtain parameters useful for the useful parameters for the individual prognosis of children who have to be operation for drug-resistant lesional epilepsy.

Key facts

Study ID

NCT04451278

Run by

Fondation Ophtalmologique Adolphe de Rothschild

People needed

200

Starts

2020-10-30

Expected to finish

2028-04-01

Last updated by the study team

2026-01-05

Who can join

Age: 6 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient aged between 6 and 18 years
• Receiving an MRI for lesional drug-resistant epilepsy
• Affiliated or beneficiary of a social security plan
• Whose parents or guardians have received information about the study and have given their express consent to participate in the study

You may not qualify if…

• Contraindication to absolute or relative MRI (in particular, pregnant or breastfeeding women)
• History of intracranial surgery
• MRI performed under general anesthesia

Where it is running

• Fondation A De Rothschild — Paris, PARIS, France (enrolling)

Full record on ClinicalTrials.gov

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