Esophagogastric Junction Distensibility During Hiatal Hernia Repair

Running, not enrolling · Not applicable

Conditions studied: Esophagogastric Junction Distensibility, Hiatal Hernia

In brief

The investigators aim to ascertain the effects of hiatal hernia repair and fundoplication on the distensibility of the esophagogastric junction (EGJ) as measured by FLIP topography/impedance planimetry. The investigators also aim to assess for any correlation between values of EGJ distensibility and GERD related quality of life (QOL) and dysphagia scores.

Key facts

Study ID

NCT04450628

Run by

Wake Forest University Health Sciences

People needed

25

Starts

2020-09-28

Expected to finish

2026-09-01

Last updated by the study team

2026-06-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient undergoing hiatal hernia repair (types I-IV included) and fundoplication
• Absence of spastic esophageal disorders (i.e. jackhammer esophagus, achalasia types I-III) assessed by preoperative high-resolution manometry
• Adult patients ≥18 years
• Elective repairs

You may not qualify if…

• Redo hiatal hernia repairs
• Emergent repairs
• Patients with contraindication to surgery or endoscopy
• Patients with esophageal varices
• Cases with insufficient esophageal length in which fundoplication is unable to be performed or a Collis gastroplasty is required
• Connective tissue diseases such as scleroderma or lupus
• Diameter measurements less than 5 mm as the EF-325N catheter is not suitable

Where it is running

• Atrium Health - Carolinas Medical Center — Charlotte, North Carolina, United States

Full record on ClinicalTrials.gov

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