Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)

Recruiting now · Not applicable

Conditions studied: Cardiovascular Disease

In brief

Cardiovascular diseases are the leading causes of death and prescription drug use. Research on certain dietary supplements looks promising as a way to help reduce risk factors. Previous studies showed that CoQ10 levels were decreased in cardiovascular patients and worsening of mitochondrial dysfunction was observed. The overall objective of this study is to determine if supplementing with CoQ10 can reduce inflammatory risk factors in adults with cardiac surgery, independent of other dietary or physical activity changes.

Key facts

Study ID

NCT04444349

Run by

Nanjing Medical University

People needed

500

Starts

2021-02-01

Expected to finish

2025-12-31

Last updated by the study team

2024-11-27

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult men and women
• Who receive cardiovascular surgery
• Agree to participate in the surgery and sign the informed consent form

You may not qualify if…

• Pregnant or planning on getting pregnant during the study
• Contain a minimum of 2 traits of metabolic syndrome
• Refused to participate in the surgery and refused informed consent

Where it is running

• Beijing Anzhen Hospital — Beijing, Beijing Municipality, China (enrolling)
• The First Affiliated Hospital of Guangzhou Medical University — Guangzhou, Guangdong, China (enrolling)
• The First Affiliated Hospital of Nanjing Medical University — Nanjing, Jiangsu, China (enrolling)
• West China Hospital of Sichuan University — Chengdu, Sichuan, China (enrolling)

Full record on ClinicalTrials.gov

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