Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Stroke, Aphasia

In brief

62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.

Key facts

Study ID

NCT04432883

Run by

University of New Mexico

People needed

50

Starts

2022-10-18

Expected to finish

2027-04-30

Last updated by the study team

2026-05-22

Who can join

Age: 25 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• aged 25-85
• must be greater than 6 months post-stroke
• must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production
• must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage
• must be stimulable for naming

You may not qualify if…

• comorbid neurological disease.
• damage to the anterior right hemisphere.
• significant mood disorder.
• substance/alcohol dependence or abuse within the past year
• presence of any implanted electrical device or contraindications to tDCS or MRI
• recent medical instability (within 4 weeks)
• pregnancy

Where it is running

• University of New Mexico Center for Brain Recovery and Repair — Albuquerque, New Mexico, United States (enrolling)

Full record on ClinicalTrials.gov

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